Enoxaparin Sodium

Enoxaparin Sodium (IP/BP/USP)


Enoxaparin is an anticoagulant, also known as a “blood thinner.” It is a type of heparin. Enoxaparin belongs to the class of drugs known as low molecular weight heparins. Enoxaparin binds to and accelerates the activity of antithrombin III. By activating antithrombin III, enoxaparin preferentially potentiates the inhibition of coagulation factors Xa and IIa. Factor Xa catalyzes the conversion of prothrombin to thrombin, so enoxaparin’s inhibition of this process results in decreased thrombin and ultimately the prevention of fibrin clot formation. Low molecular weight heparins are less effective at inactivating factor IIa due to their shorter length compared to unfractionated heparin.

Enoxaparin Sodium is used to prevent and treat harmful blood clots. This helps to reduce the risk of a stroke or heart attack. This medication helps keep your blood flowing smoothly by lowering the activity of clotting proteins in the blood. It is used to treat and prevent deep vein thrombosis (DVT) and pulmonary embolism (PE) including during pregnancy and following certain types of surgery. It is also used in those with acute coronary syndrome (ACS) and heart attacks. It is given by injection just under the skin or into a vein. Other uses include inside kidney dialysis machines.

Enoxaparin is used to prevent blood clots in the leg in patients who are on bedrest or who are having hip replacement, knee replacement, or stomach surgery. It is used in combination with aspirin to prevent complications from angina (chest pain) and heart attacks. It is also used in combination with warfarin to treat blood clots in the leg. Enoxaparin is in a class of medications called low molecular weight heparins. It works by stopping the formation of substances that cause clots.

Bacto Chem Plant Capacity:
1200 kgs

Grade:
Injectable

Specification:
BP/EP/USP/IP

Enoxaparin Sodium Injection is indicated for:

    • Enoxaparin is indicated for the prevention of ischemic complications in unstable angina and in non Q-wave myocardial infarction; it is indicated in conjunction with percutaneous intervention and/or other treatment for the management of acute ST elevation myocardial infarction.
    • Enoxaparin is also indicated in the prophylaxis of DVT in abdominal surgery, hip replacement, knee replacement, or medical patients with severely restricted mobility during acute illness. Additionally, enoxaparin is indicated for the inpatient treatment of DVT with or without pulmonary embolism and the treatment of outpatient DVT without pulmonary embolism.

Structure of Enoxaparin Sodium

Enoxaparin Sodium from Bacto Chem

Bacto Chem is one of the only companies to manufacture bovine sourced Enoxaparin Sodium from biomass in India. Our product follows the Indian Pharmacopeial standards, and our product has a potency of 160 IU/mg to match the global potency values of bovine Heparin Sodium.

All Bacto Chem Products are manufactured in compliance with the World Health Organization (WHO) Current Good Manufacturing Practices (cGMP) under strict conditions in state-of-the-art facilities. This results in products that are consistently produced and controlled to the quality standards appropriate to their intended use and as required by the product specification. Each of our products is manufactured in a dedicated block with no cross-contamination.
Our strengths lie in our highly trained and experienced QC department which ensures all the raw materials go through stringent testing prior to their utilisation, ensuring that only raw materials of the highest quality are used only after approval from QC. We ensure that all our equipment and manufacturing process are thoroughly validated and updated. We invest heavily on training our production and QC teams to understand and monitor every stage of the production cycle to ensure safety and highest quality product. Maintaining cleanliness is our responsibility, and we always focus on ensuring proper measures are taken to follow our validates cleaning protocols to avoid batch to batch contamination.
Additionally, Bacto Chem is compliant with the requirements of OHSAS 18001:2007 in occupational health and safety management systems. Bacto Chem is also ISO 14001:2015 certified which recognizes us as an organization seeking to manage its environmental responsibilities in a systematic manner that contributes to the environmental pillar of sustainability and has the necessary Halal certifications as well.