Chenodeoxycholic Acid

Chenodeoxycholic Acid

Chenodeoxycholic Acid is a bile acid naturally found in the body. This product is a derivative of the Cholic Acid API and is the first derivative from Cholic Acid, is the first in a large list of cholic acid derivatives. Chenodeoxycholic acid (or Chenodiol) is an epimer of ursodeoxycholic acid.
Chenodeoxycholic acid is a bile acid naturally found in the body. Chenodeoxycholic acid is a bile acid mainly found in the bile of vertebrates and mammals. Initially isolated from the bile of domestic geese, chenodeoxycholic acid is a type of carboxylic acid typically used to treat gallstones.
Along with cholic acid, chenodeoxycholic acid sodium salt is one of two primary human bile acids. Chenodeoxycholic acid contains two hydroxyl groups and is altered by adding another hydroxyl group to create cholic acid.
Chenodeoxycholic acid is produced as a white crystalline substance. It is not soluble in water, however can be dissolved in acetic acid and alcohol, and has a 165–167 °C melting point.

It works by dissolving the cholesterol that makes gallstones and inhibiting production of cholesterol in the liver and absorption in the intestines, which helps to decrease the formation of gallstones. It can also reduce the amount of other bile acids that can be harmful to liver cells when levels are elevated. It works by dissolving the cholesterol that makes gallstones and inhibiting production of cholesterol in the liver and absorption in the intestines, which helps to decrease the formation of gallstones.
Chenodeoxycholic acid is indicated for the treatment of inborn errors of primary bile acid synthesis due to sterol 27 hydroxylase deficiency (presenting as cerebrotendinous xanthomatosis (CTX)) in infants, children and adolescents aged 1 month to 18 years and adults. Chenodeoxycholic Acid is indicated for patients with radiolucent stones in well-opacifying gallbladders, in whom selective surgery would be undertaken except for the presence of increased surgical risk due to systemic disease or age. Chenodeoxycholic Acid will not dissolve calcified (radiopaque) or radiolucent bile pigment stones.

Structure of Chenodeoxycholic Acid

Chenodeoxycholic Acid from Bacto Chem

Bacto Chem’s Chenodeoxycholic acid is manufactured domestically in India Using Indian bovine-source Bile, which is used to manufacture cholic acid, the key starting material in the manufacturing process of UDCA. Our patented manufacturing process gives us an edge over our competitors owing to our process’ superiority in terms of yield and quality.
Indian cattle are often recognised and believed to be better for human consumption because:
Absence of Bovine Spongiform Encephalopathy (BSE), or Mad Cow Disease
• BSE is caused in cattle when the animals are fed with meat or bone meal. Protein cells become twisted into prions. Prions are NOT DESTROYED by fire, freezing, disinfectants, sterilization procedures or radiation.
• Indian cattle are grass fed, this factor removes the possibility of these cattle encountering BSE,
• Cholic Acid prepared from Indian cattle is free of BSE/TSE.
Greater bioavailability:
• Bovine sourced proteins and APIs show greater affinity of binding with human cells to show greater affinity of binding, showing greater efficacy.

All Bacto Chem Products are manufactured in compliance with the World Health Organization (WHO) Current Good Manufacturing Practices (cGMP) under strict conditions in state-of-the-art facilities. This results in products that are consistently produced and controlled to the quality standards appropriate to their intended use and as required by the product specification. Each of our products is manufactured in a dedicated block with no cross-contamination.
Our strengths lie in our highly trained and experienced QC department which ensures all the raw materials go through stringent testing prior to their utilisation, ensuring that only raw materials of the highest quality are used only after approval from QC. We ensure that all our equipment and manufacturing process are thoroughly validated and updated. We invest heavily on training our production and QC teams to understand and monitor every stage of the production cycle to ensure safety and highest quality product. Maintaining cleanliness is our responsibility, and we always focus on ensuring proper measures are taken to follow our validates cleaning protocols to avoid batch to batch contamination.
Additionally, Bacto Chem is compliant with the requirements of OHSAS 18001:2007 in occupational health and safety management systems. Bacto Chem is also ISO 14001:2015 certified which recognizes us as an organization seeking to manage its environmental responsibilities in a systematic manner that contributes to the environmental pillar of sustainability and has the necessary Halal certifications aswell.

All Bacto Chem Products are manufactured in compliance with the World Health Organization (WHO) Current Good Manufacturing Practices (cGMP) under strict conditions in state-of-the-art facilities. This results in products that are consistently produced and controlled to the quality standards appropriate to their intended use and as required by the product specification. Each of our products is manufactured in a dedicated block with no cross-contamination.
Our strengths lie in our highly trained and experienced QC department which ensures all the raw materials go through stringent testing prior to their utilisation, ensuring that only raw materials of the highest quality are used only after approval from QC. We ensure that all our equipment and manufacturing process are thoroughly validated and updated. We invest heavily on training our production and QC teams to understand and monitor every stage of the production cycle to ensure safety and highest quality product. Maintaining cleanliness is our responsibility, and we always focus on ensuring proper measures are taken to follow our validates cleaning protocols to avoid batch to batch contamination.
Additionally, Bacto Chem is compliant with the requirements of OHSAS 18001:2007 in occupational health and safety management systems. Bacto Chem is also ISO 14001:2015 certified which recognizes us as an organization seeking to manage its environmental responsibilities in a systematic manner that contributes to the environmental pillar of sustainability and has the necessary Halal certifications as well.